Описание: Paralytic Shellfish Toxins (PST) are potent neurotoxins produced by several species of phytoplankton, and may bio-accumulate in filter-feeding shellfish. Human consumption of contaminated shellfish can result in Paralytic Shellfish Poisoning (PSP). As a result, monitoring of PST in shellfish is a statutory requirement in many regions of the world, including the EU. However, the detection of PSTs is challenging, due to their highly polar hydrophilic nature and the large number of structurally similar congeners.
Tetrodotoxin (TTX) is another low molecular weight toxin thought to be produced by marine bacteria, which has been found to accumulate in bivalve shellfish. While TTX is not yet stipulated in the EU regulatory requirements, it is known to be as toxic as some analogs of PST.
Monitoring TTX along with other PSTs in shellfish could further protect public health. However, current methodologies used in control labs (including LC/FLD) are not suitable for its detection, and these labs do not have spare resources to add a further test. A method that can detect all PSTs and TTX together in one analytical method would be advantageous for monitoring the risk from all these hydrophilic marine toxins.
In this webinar, we’ll discuss the development of a combined method to ensure the high quality of shellfish, intended for human consumption, using hydrophilic interaction liquid chromatography with tandem mass spectrometry (HILIC/MS/MS) and MassHunter software.
Лектор: Andrew D. Turner (Principal Chemist, Food Safety Group, Cefas Weymouth Laboratory, UK)
As Principal Chemist in the Cefas Weymouth Food Safety Group, Andrew is responsible for the marine biotoxin testing in shellfish performed on behalf of the UK government competent authorities. He oversees the development and implementation of new methods for food safety surveillance and leads the development of research activities of the chemistry team.
Дата: 3 декември 2019, 17:00 ч. и 4 декември, 10:00 ч.
Продължителност: 1 час