Ultivo triple quadrupole LC/MS (LC/TQ)

Ultivo is a stackable Liquid Chromatography Triple Quadrupole (LC/TQ) mass spectrometer that eliminates the MS footprint by incorporating the MS into the LC stack, and represents a transformative approach to LC/TQ. Ultivo triple quadrupole LC/MS provides the performance found in larger comparable systems, but at a fraction of their size. 

Innovations such as the Vortex Collision Cell, Cyclone Ion Guide, and VacShield provide users the sensitivity, robustness, reliability, and performance required for the day-in, day-out challenges of high-throughput sample analysis. Now with the addition of an ESI-only model, and features geared to assist you with 21 CFR Part 11 compliance, the Ultivo LC/TQ continues to reshape expectations, reinvent capabilities, and redefine what’s possible when small meets powerful.

  • Smallest footprint of any LC/TQ on the market, delivering a price-performance per square foot ratio that leads to reduced costs and the fastest path to achieving ROI.
  • Multiple ion source configurations available, including Agilent Jet Stream and traditional ESI
  • Instrument innovations for enhanced results:
    • VacShield – eliminates the need to vent the system while performing ion injector maintenance so instrument maintenance downtime is minimized and laboratory efficiency is increased.
    • Cyclone Ion Guide – compresses the ion beam without loss of signal, resulting in higher ion transmission efficiencies and enhanced data quality.
    • Vortex Collision Cell – provides efficient dissociation of ions in the cell, improved focusing and transmission of ions, rapid clearance of the cell between mass transitions, thereby allowing for more MRMs/sec, zero crosstalk and greater confidence in results by removing noisy background.
  • Screen, confirm and quantitate – Triggered MRM (tMRM) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for compound screening and confirmation.
  • The intuitive operational design of the “Quant-My-Way” software feature and the MassHunter Productivity App provide boosts in productivity by up to 40%: require less need for operator training, reduce time reviewing data and simplify report generation.
  • Enhanced Maintenance Feedback (EMF) features centered on smart, self-aware diagnostics ensure optimum uptime and help to drive down maintenance costs
  • Combine with MassHunter software, OpenLab ECM 3 series (3.5 and above software) and IQ/OQ services provide data integrity tools to assist you in achieving compliance readiness.
  • Optimized for unparalleled performance and advanced efficiency when paired with Agilent’s market leading portfolio of analytical LC systems and associated consumables.
  • Put CrossLab services to work for you; consultative support for workflow enablement, lab analytics, compliance, inventory management, asset management and relocation services


Incredibly Powerful, Remarkably Efficient Quantitation

MassHunter Productivity App for Targeted Pesticides Screening by LC/TQ

Brochures, English, 09 Nov 2018, 2.08 MB, PDF


Ultivo Triple Quadrupole Mass Spectrometer Brochure

Ultivo Triple Quadrupole Mass Spectrometer

Brochures, English, 29 Oct 2018, 10.71 MB, PDF


Application Notes:

Meeting California Cannabis Regulations with the Agilent 1260 Infinity II Prime LC and Agilent Ultivo Triple Quadruple MS

A method from Weck Labs for assessing pesticides, mycotoxins, and potency in cannabis flowers.

Application Notes, English, 13 May 2019, 809.16 KB, PDF


Determination of Pesticides and Mycotoxins as defined by California State Recreational Cannabis Regulations

A robust LC/MS/MS method and sample preparation workflow for the determination of pesticide and mycotoxin content for cannabis dried flower samples.

Application Notes, English, 05 Mar 2019, 5.30 MB, PDF


Analysis of Amino Acids in Animal Feed Matrices Using the Ultivo Triple Quadrupole LC/MS System

A simple analytical method for the quantitation of underivatized amino acids using HILIC-Z and Ultivo

Application Notes, English, 01 Feb 2019, 1.12 MB, PDF


LC/MS/MS Determination of PFOS and PFOA in Water and Soil Matrices

Application of Ultivo LC/TQ for determination of PFOS and PFOA in environmental water and soil.

Application Notes, English, 25 Jan 2019, 772.19 KB, PDF


Analytical Determination of Drugs in Serum Using the Ultivo Triple Quadrupole LC/MS

This Application Note demonstrates a sensitive and precise method for analyzing eight drugs in serum on the Agilent Ultivo triple quadrupole LC/MS system.

Application Notes, English, 24 Jan 2019, 919.88 KB, PDF


Quick and Routine Research Quantification in Melatonin in Plasma with Agilent Ultivo LC/TQ

Research quantification of melatonin (MEL) with Agilent 1260 Infinity II Prime LC system coupled with Agilent Ultivo triple quadrupole LC/MS ESI source

Application Notes, English, 08 Jan 2019, 479.23 KB, PDF


Veterinary Drug Detection in Pork and Milk

A 10 minute analytical method for the precise quantification of 12 regulated veterinary drug compounds in pork and milk.

Application Notes, English, 26 Dec 2018, 1.03 MB, PDF


Multiresidue Pesticides Screening and Quantitation in Complex Food Matrices Using an Agilent Ultivo Triple Quadrupole LC/MS

Sensitive detection of more than 250 pesticide residues in foods using the Agilent Ultivo Triple Quadrupole LC/MS system

Application Notes, English, 26 Mar 2018, 651.86 KB, PDF


Analysis of microcystins and nodularin in drinking water using an Agilent Ultivo triple quadrupole LC/MS

A sensitive and robust method for the analysis of microcystins and nodularin in drinking water.

Application Notes, English, 19 Mar 2018, 567.94 KB, PDF


Analysis of mycotoxins in food matrices using the Agilent Ultivo Triple Quadrupole LC/MS

A sensitive and precise method for the analysis of mycotoxins in foods.

Application Notes, English, 22 Feb 2018, 803.96 KB, PDF