Agilent 7250 GC/Q-TOF

The Agilent 7250 GC/Q-TOF system delivers full-spectrum, high-resolution, accurate-mass data with a wide dynamic range for identifying and quantifying GC-amenable compounds. This high-resolution GC/Q-TOF enables accurate mass screening by GC/MS and enhanced compound identification through MS/MS, low energy electron ionization and complimentary chemical ionization techniques.

Whether being used in complex metabolomics studies, pesticide screening in challenging matrices, or compound identification in herbal extracts, quadrupole time-of-flight GC/MS provides the ultimate in performance. Designed for real-world analysis and built for laboratory robustness, this accurate mass screening GC/MS delivers what your organization needs – consistently confident results, allowing you to see the whole picture.


  • Identifies compounds through high-resolution, accurate-mass data and sensitive detection.
  • Quantifies analytes accurately across a wide dynamic range, without compromising spectral quality.
  • Simplifies ambiguous data with low-energy EI for softer ionization and molecular ion enhancement (application specific).
  • Supports complimentary data types with available chemical ionization for both positive and negative mode analyses
  • Increases confidence in compound detection with highly efficient ionization and MassHunter’s SureMass algorithm for accurate and sensitive extraction of library-quality compound spectra for high match scores.
  • Enhances compound identification with spectral fidelity for trustworthy library matching and isotopic fidelity for generating verifiable chemical formulas.
  • Detects trace-level target compounds in the presence of more abundant matrix compounds with a wide in-spectrum dynamic range.
  • Elucidates chemical structures with MS/MS capabilities and Molecular Structure Correlator software that reveals greater detail.
  • Ensures excellent data quality even for narrow chromatographic peaks in high-throughput workflows with data acquisition rates of up to 50 spectra per second.
  • Performs screening, profiling, discovery workflows, and more, using comprehensive MassHunter software.
  • Drive productivity with the NEW 8890 GC’s built-in intelligence for diagnostics and monitoring, and simplified access to powerful operations through the integrated touchscreen and browser interface.
  • Supports both flow and thermally-modulated comprehensive GCxGC for flexibility in enhanced chromatographic resolution for selective compound detection.

Screening for Hundreds of Pesticide Residues Using a GC/Q-TOF with an Exact Mass Pesticide Database in Food

The Agilent 7200 GC/Q-TOF was used to rapidly screen, identify, and generate quantitative information for pesticide residues in five different food matrices.

Application Notes, English, 30 Jan 2019, 2.28 MB, PDF

Screening for More Than 740 Pesticide Residues in Food Using an Agilent 7200 GC/Q-TOF

Organically grown fruit and vegetable samples were extracted using the EN QuEChERS method

Application Notes, English, 21 Jan 2019, 3.58 MB, PDF

Combination of Chemcial Ionization (CI) and Low Energy Ionization (EI) Capabilities with High-Resolution Q-TOF GC/MS

Important applications for high-resolution GC/MS systems include untargeted screening approaches as well as unknown compound identification.

Application Notes, English, 24 Oct 2018, 2.97 MB, PDF

Analysis of Extractable and Leachable (E&L) Compounds Using a Low-Energy EI-Capable High‑Resolution Accurate Mass GC/Q-TOF

This work presents a novel tool to study E&L compounds with enhanced flexibility and confidence using a high-resolution accurate mass GC/Q-TOF

Application Notes, English, 23 Oct 2017, 1.11 MB, PDF

Metabolic Changes in Lung Tissue of Tuberculosis-Infected Mice Using GC/Q-TOF with Low Energy EI

An untargeted metabolomics study was done using a novel high-resolution 7250 GC/Q-TOF to confirm the molecular ions and identify molecular formulas of unknowns.

Application Notes, English, 11 Jul 2017, 3.22 MB, PDF