6530 LC/Q-TOF

Raise your analysis to a new level with the Agilent 6530 Quadrupole Time-of-Flight LC/MS system. The 6530 delivers the power of high-resolution, accurate-mass MS/MS, so you can be fully confident of your data.

  • Mass accuracy within 2 ppm gives you complete confidence in your analysis.
  • Powerful Agilent Jet Stream source enables you to uncover low level components.
  • Wide in-spectrum dynamic range facilitates simultaneous measurement of minor components in the presence of intense background interferences. 
  • The latest developments in Agilent Infinity II UHPLC, 2D-LC, SFC, and even GC-APCI chromatographic interfaces give you blazing fast acquisition speed.
  • Powerful MassHunter software provides the latest software capabilities for profiling, characterizing, identifying, and quantifying compounds in complex mixtures via high-definition MS and MS/MS.
  • Check out the latest developments in untargeted screening and quantitation using Agilent’s All Ions MS/MS technique.


Raise Your Analysis to a New Level

Agilent 6530 Q-TOF LC/MS system

Brochures, English, 13 Apr 2018, 653.39 KB, PDF


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Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS

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An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies

This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.

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Measuring Drug-to-Antibody Ratio (DAR) for Antibody-Drug Conjugates (ADCs) with UHPLC/Q-TOF

In this application note, we are investigating an antibody drug conjugate (ADC) with a cysteine linker. The Agilent 1290 Infinity II liquid chromatography system connected to a PLRP-S reversed phase liquid chromatography column was used to separate restored light and heavy chains and light and heavy chains of the corresponding drug linkers.

Application Notes, English, 16 Sep 2016, 710.02 KB, PDF


Clone Selection Using the Agilent 1290 Infinity Online 2D-LC/MS Solution

Clone selection is important during Monoclonal antibodies development. Proof of principle using 2D-LC/MS solution is demonstrated for identifying the correct clone.

Application Notes, English, 14 Sep 2016, 2.75 MB, PDF